Max Planck Florida’s Neurotransmissions Podcast

Max Planck Florida’s Neurotransmissions Podcast

Neuroscience stories from the lab and life: By scientists, for everyone. Max Planck Florida Institute for Neuroscience (MPFI) researchers Ben Scholl, Ph.D., Joe Schumacher, Ph.D., Jeremy Chang, Ph.D, and Misha Smirnov, Ph.D. host Neurotransmissions: an engaging, accessible look inside the neuroscience research world, exploring current research topics and emerging technologies, public health issues in the domain of biomedical science, the intersection between science and society, and unique perspectives and experiences across generations of neuroscientists. Production and communication support by Dr. Helena Decker, Katie Edwards and Kevin Albertini.

Max Planck Florida Institute for Neuroscience Science 64 rész Neuroscience stories from the lab and life: By sc…
63 - Dr. Peter Dayan and Computational Neuroscience
43 perc 64. rész Max Planck Florida Institute for Neuroscience
How can quantitative methods help us understand how the brain works? On this episode Joe, Jeremy, and Alex are joined by Dr. Peter Dayan the director of the Max Planck Institute for Biological Cybernetics in Tubingen, Germany. They'll discuss the different computational approaches taken to understand how the brain works, Dr. Dayan's own work using models to understand reinforcement learning and the role of the neurotransmitter dopamine in this process, and the goal of the International Brain Laboratory. Enjoy!
62 - Dr. Rodrigo Quian Quiroga, NeuroScience Fiction and Conciousness
55 perc 63. rész Max Planck Florida Institute for Neuroscience
In this episode, Joe and Misha talk to Dr. Rodrigo Quian Quiroga, author of the new book “NeuroScience Fiction” and researcher who famously identified the Jennifer Aniston neuron. They dive into everything from Dr. Quiroga’s work with concept cells to his fascinating look at the convergence of neuroscience with futuristic sci-fi. They also explore the evolution of AI and what it means to have consciousness.
61 - Feedforward and Feedback Loops in the Visual System
41 perc 62. rész Max Planck Florida Institute for Neuroscience
On this episode Jeremy and new guest co-host Alex Gribizis chat with Dr. W. Martin Usrey, Professor and Chair of the Department of Neurobiology, Physiology, and Behavior and the University of Davis. With Dr. Usrey we learn more about the structure of the visual system, the interactions between these different structures, and things Dr. Usrey has learned along the way about mentorship.
Podcast - Black In Neuro With Dr. Kaela Singleton
35 perc 61. rész Max Planck Florida Institute for Neuroscience
In this episode, Joe and Misha talk with Kaela Singleton, Postdoctoral Fellow in the Department of Cell Biology at Emory University and co-founder and president-elect of Black in Neuro. We learn about her research into Menkes Disease, how her career in science has evolved throughout the years, and the work she is doing to help raise visibility and cultivate opportunities for black neuroscientists through the #BlackinNeuro movement.
59 - The Future of Targeted Therapies for Autism with Dr. Peter Tsai
42 perc 60. rész Max Planck Florida Institute for Neuroscience
How does the clinic influence the bench? Joe, Jeremy, and Audrey are joined by Dr. Peter Tsai Assistant Professor in the departments of Neurology and Neurotherapeutics, Neuroscience, Pediatrics, and Psychiatry at UT South Western. Learn how Dr. Tsai's experience in the clinic led him down a path of investigating the surprising role of the cerebellum in autism spectrum disorder and how Dr Tsai's findings in the lab could impact the development of future treatments.
58 - Arc and Intercellular Signaling with Dr. Jason Shepherd
50 perc 59. rész Max Planck Florida Institute for Neuroscience
How did an ancient virus help shape the human brain? In this episode, Joe and Jeremy sit down with Dr. Jason Shepherd, Assistant Professor of Neurobiology and Anatomy, Biochemistry and Opthalmology & Visual Sciences at the University of Utah School of Medicine, to discuss the role of Arc (activity-regulated cytoskeleton-associated protein) in the regulation of synaptic plasticity. Learn also how Dr. Shepherd and his group discovered a possible new role for Arc in transcellular signaling that may indicate its origin as an ancient retrovirus that integrated into the genome. If you can bear the puns, this episode packs a fascinating story of a career bridging molecular and in vivo processes and an unanticipated discovery.
57- Behavioral Time Scale Synaptic Plasticity with Dr. Jeff Magee
30 perc 58. rész Max Planck Florida Institute for Neuroscience
Cells that fire together wire together. Hebbian mechanisms of plasticity, summarized by that simple phrase, have dominated the field of learning and memory for decades. However, they present limitations when applied to many behavioral paradigms. On this episode Jeremy, Audrey, and Andre sit down with Dr. Jeff Magee, Howard Hughes Medical Institute Investigator, The Cullen Foundation Distinguished Endowed Chair at the Jan and Dan Duncan Neurological Research Institute, and Professor in the Department of Neuroscience at Baylor College of Medicine. They'll discuss how Dr. Magee's work looking at dendritic processes led him and his group to discover a new plasticity paradigm, in place field learning that breaks from traditional Hebbian rules. Hear also how Dr. Magee keeps active in the lab and his advice for young investigators.
56: Scientific Funding at the National Science Foundation with Dr. Kurt Thoroughman
23 perc 57. rész Max Planck Florida Institute for Neuroscience
On the final episode recorded live from the Society for Neuroscience Conference 2019, Jeremy sits down with Dr. Kurt Thoroughman, Associate Professor in the Department of Biomedical Engineering at Washing University in St. Louis, and Director of the National Science Foundation's (NSF) Cognitive Neuroscience program. Learn about how NSF is structured, the role of a program director, how a grant application is evaluated, and the opportunities available for trainees.
55- SfN 2019: NINDS Building Up the Nerve with Dr. Lauren Ullrich
34 perc 56. rész Max Planck Florida Institute for Neuroscience
At the 2019 Society for Neuroscience Conference in Chicago Misha catches up with an old friend of the podcast Dr. Lauren Ullrich (Ep #13), Scientific Program Manager at the National Institute of Neurological Disorders and Stroke. Learn about the process of applying for funding from the NIH and how Dr. Ullrich's new podcast 'Building up the Nerve' is giving a peek into the life cycle of a grant.
54- SfN2019: Journal of Neuroscience, Mentorship, & Nicotine Addiction with Dr. Marina Picciotto
26 perc 55. rész Max Planck Florida Institute for Neuroscience
Our series of interviews at the Society for Neuroscience Conference 2019 in Chicago keeps on rolling as Jeremy sits down with Dr. Marina Picciotto Charles B.G . Murphy Professor of Psychiatry and Professor in the Child Study Center of Neuroscience and of Pharmacology, Deputy Chair for Basic Science Research in the Dept of Psychiatry, Deputy Director of the Kavli Institute for Neuroscience at Yale University, and Editor in Chief of the Journal of Neuroscience. They'll chat about how the Journal of Neuroscience supports the Society for Neuroscience, publishing in and training opportunities at the Journal of Neuroscience, Dr. Picciotto's approach to mentorship, and her lab's work looking at nicotine addiction. Enjoy!
53- SfN 2019: Backyard Brains with Drs. Greg Gage and Etienne Serbe
22 perc 54. rész Max Planck Florida Institute for Neuroscience
The neuro-revolution is coming. In this episode Jeremy sits down with Drs. Greg Gage and Etienne Serbe in Chicago from Backyard Brains. From an exciting challenge centered around the SfN conference to programs centered around designing new experiments, learn about how Backyard Brains is bringing new opportunities to learn about neuroscience to the next generation of scientists.
52 - SfN 2019: Pathways to Graduate School with Tavita Garrett
34 perc 53. rész Max Planck Florida Institute for Neuroscience
Once again Neurotransmissions traveled to the annual Society for Neuroscience conference to chat with some new and old friends. In the first episode of our five-part miniseries, Misha is joined by Tavita Garrett former MPFI post-baccalaureate and current graduate student at Oregon Health & Science University to chat about postbac programs, the path to graduate school, and the joys of electrophysiology. But first, we're joined by previous guest co-host Dr. Paul Evans and current MPFI Head of Scientific training to learn more about the MPFI postbac program (formerly the PRE program) and upcoming deadlines for applications.
51: Ion Channels and Synapses with Dr. Bert Sakmann
23 perc 52. rész Max Planck Florida Institute for Neuroscience
Our two-part series of interviews with Dr. Bert Sakmann continues as he explains to Joe and Misha how he got interested in neuroscience, his work on characterizing ion channels, the finer points of electrophysiology and the importance of synapses. If you have not had a chance yet, make sure to check out part one of our conversation with Dr. Sakmann.
50 (Part One): Building MPFI with Dr. Bert Sakmann
28 perc 51. rész Max Planck Florida Institute for Neuroscience
How does a Max Planck Institute end up in Florida? On this special 50th episode we have the first part of a two-part series of interviews recorded in June 2016, with Dr. Bert Sakmann, Nobel Prize Recipient and the Inaugural Scientific Director of Max Planck Florida Institute for Neuroscience. Joe and Misha sit down with Dr. Sakmann as he recounts the early days of Max Planck Florida: kiteboarding, recruiting scientists to the institute and developing a scientific program.
Ep 49 - Language: Constructing Knowledge Beyond Words with Dr. David Poeppel
47 perc 50. rész Max Planck Florida Institute for Neuroscience
How does language get processed in the brain? New research is taking our understanding of how the brain processes language and speech beyond Broca and Wernicke's areas. This week Joe and Misha are joined by Dr. David Poeppel Director of the Department of Neuroscience at the Max Planck Institute for Empirical Aesthetics in Frankfurt and Professor of Psychology and Neural Science at New York University to discuss the finer details of language.
48- Electrophysiology and Cell Types with Dr. Bernardo Rudy
32 perc 49. rész Max Planck Florida Institute for Neuroscience
In this episode, Misha and Andre are joined by Dr. Bernardo Rudy, Valentino D.B. Mazzia, MD, JD Professor of Anesthesiology, Department of Anesthesiology, Perioperative Care, and Pain Medicine and Professor, Department of Neuroscience and Physiology at New York University. Learn the curious path Dr. Rudy took to obtaining two PhDs, his labs work on the types and roles of cortical interneurons and the challenges that still remain in classifying types of neurons.
47: How Visual is the Visual Cortex? with Dr. Nathalie Rochefort
30 perc 48. rész Max Planck Florida Institute for Neuroscience
How visual is the visual cortex? In this episode, Joe and Jeremy are joined by Dr. Nathalie Rochefort, Sir Henry Dale Fellow and Chancellor's Fellow at the Centre for Discovery Brain Sciences at the University of Edinburgh to discuss why long-held views about the function of the visual cortex are being challenged today. Learn how Dr. Rochefort went from studying the history of sciences to making her own new discoveries and how new approaches are allowing her team and others to understand functions of the visual cortex beyond vision.
46: Connectomics with Dr. Moritz Helmstaedter
40 perc 47. rész Max Planck Florida Institute for Neuroscience
What approaches are researchers taking to understand which neurons talk to each other in the brain? Joe and Misha sit down with Dr. Moritz Helmstaedter, Scientific Director and Head of the Department of Connectomics at the Max Planck Institute for Brain Research in Frankfurt Germany. They'll discuss the current state of connectomics, the approaches researchers are taking, the challenges of working with the large datasets necessary to understand neuronal connections, and the work that Dr. Helmstaedter's group is doing with electron microscopy to map the connections within the brain.
45 - Counting Neurons with Dr. Roberto Lent
44 perc 46. rész Max Planck Florida Institute for Neuroscience
We dug up another episode from our archive for you to enjoy this week. Misha, Joe, and guest co-host Dr. Helena Decker, MPFI's Head of Scientific Communications, sit down with Dr. Roberto Lent, head of the Laboratory for Neuroplasticity of the Institute of Biomedical Sciences, Federal do Rio de Janeiro. They will discuss Dr. Lent's efforts in counting the neurons of the brain, the concept of the disconnectome, and the work Dr. Lent is doing in science outreach and education.
44 - The Human Brain with Pierre Vanderhaeghen
36 perc 45. rész Max Planck Florida Institute for Neuroscience
Joe and Andre sit down with Dr. Pierre Vanderhaeghen, Group leader at VIB research institute. Learn about what makes the human brain special methods that Dr. Vanderhaeghen's group uses to investigate the development of the human brain, and how the preservation of early traits through adulthood could play a role in making the human brain adaptable.
43- The Brain from Inside Out with Dr. Gyorgy Buzsaki
34 perc 44. rész Max Planck Florida Institute for Neuroscience
On this episode Joe and first time co-host Jeremy Chang sit down with Dr. Gyorgy Buzsaki, Biggs Professor of Neuroscience at New York University. They explore the types of oscillatory activity that occurs within the brain and how this activity may aid in the packaging of information within the brain. They also discuss the classical empiricists viewpoint of the brain and how approaching the questions of how the brain works can be benefited by taking an inside-out viewpoint that looks at how the brain predicts and interacts with the external world and the importance of sharing data. We hope you enjoy this wide-ranging episode, and Dr. Buzsaki's open data sets can be found at www.buzsakilab.com.
42- A New Zealander in Germany with Dr. Jason Kerr
51 perc 43. rész Max Planck Florida Institute for Neuroscience
On this episode, we returned to our vault and found this March 2016 discussion (our first recording ever!), where Joe, Misha, and Ben were joined by Dr. Jason Kerr, Director of the Department of Behavior and Brain Organization the Center of Advanced European Studies and Research (caesar). In a wide-ranging conversation, they’ll discuss the adventure in neuroscience that would end up with a New Zealander living in Germany, what it is like to be a group leader and director in the Max Planck system, the importance of studying natural behaviors and dive deep into the specialization of the visual system across species.
41- SFN 2017 Dr. Christine Constantinople and Dr. Matthew Lovett-Baron
27 perc 42. rész Max Planck Florida Institute for Neuroscience
On our final episode recorded at SfN 2017, Joe sits down with Dr. Christine Constantinople, now Assistant Professor at New York University, to discuss risk-reward learning and starting up a lab. Then Joe sits down with Dr. Matthew Lovett-Baron, postdoctoral fellow at Stanford University and soon to be Assistant Professor in the Neurobiology section at UCSD, to discuss his work using zebrafish the look at the role of neuromodulation in the regulation of escape behavior.
40: SFN 2017 Podcast #2 Bridget Queenan
22 perc 41. rész Max Planck Florida Institute for Neuroscience
Our series of in the field recordings from SfN 2017 continues as Misha gets a chance to catch up again with Dr. BN Queenan (Episode 13), associate director of the UCSB Brain Initiative, to chat about the role of institutional and implicit biases in the gender inequality in academia.
39: SFN 2017 Traumatic Brain Injury with Dr. Mark Burns
20 perc 40. rész Max Planck Florida Institute for Neuroscience
Once again the podcast hit to road to meet up with new and old friends to talk all things neuroscience at the 2017 SfN meeting in Washington D.C. This week Misha sat down with Dr. Mark Burns, Associate Professor of Neuroscience at Georgetown University, to discuss traumatic brain injury and chronic traumatic encephalopathy.
38: Associative Learning in the Amygdala with Dr. Andreas Lüthi
25 perc 39. rész Max Planck Florida Institute for Neuroscience
How do you learn the appropriate response to a fear-inducing stimulus? Misha and Andre are joined on this episode by Dr. Andreas Lüthi, Group Leader at the Friedrich Miescher Institute for Biomedical Research in Basel Switzerland to discuss the role of the amygdala in attributing emotional significance to external stimuli and the generation of appropriate responses. Learn more about how Dr. Luthi and are combining new techniques to further dissect how the local circuits within the amygdala allow appropriate responses to be learned.
Episode 37: Synaptic Organizers with Dr. Hisashi Umemori
26 perc 38. rész Max Planck Florida Institute for Neuroscience
On this episode, Michael is joined by former MPFI Post-Baccalaureate Research Experience (PRE) Fellow Amber Luongo and Dr. Hisashi Umemori, associate professor of neurology at Harvard Medical School. Dr. Hisashi studies synaptic connections between neurons and how they established, refined and maintained in the nervous system. Learn more about Dr. Hisashi identifies molecules he calls synaptic organizers and the possible translational applications these molecules could have in treating neurological disorders.
36: Meditation, Predation, and Octopuses with Dr. Cris Niell
29 perc 37. rész Max Planck Florida Institute for Neuroscience
On this episode, Joe and Misha are joined by Dr. Cris Niell, Associate Professor in the Department of Biology at the University of Oregon. Learn how Dr. Niell is looking at the effects of meditation in the brain, how he got interested in the visual system of the mouse, the work his lab has done on predatory behavior, and why he’s expanding into the looking at the visual system of the octopus. We’ll also finally answer the age-old question: is it octopuses or octopi?
35: Wiring up the Brain, Society for Neuroscience, and Graduate School with Dr. Carol Mason
50 perc 36. rész Max Planck Florida Institute for Neuroscience
On this episode we’re digging back into the vault to a Spring 2016 conversation Joe, Misha, and Ben had with Dr Carol Mason Professor of Pathology and Cell Biology, Neuroscience and Ophthalmic Science at Columbia University and former Society for Neuroscience President. Topics they’ll cover include the work Dr. Mason’s group is doing looking how the brain wires together during early development, the evolving landscape of neuroscience research over the years, and Dr. Mason’s advice for prospective graduate students.
34: Nature vs Nurture with Dr. Liqun Luo
30 perc 35. rész Max Planck Florida Institute for Neuroscience
What is it that defines us, nature or nurture? Michael and Andre sit down with Liqun Luo, Professor of Biology at Stanford University, to discuss the role of genetics and experience in the development of the brain. As a trained geneticist Dr. Luo uses both flies and mice to investigate the development of the nervous system. Learn more about how the olfactory system differs from other sensory modalities and the genetic tools Dr. Luo is developing and using to help investigate the roles genes play in the construction of neural circuits.
33: The Plastic Brain with Dr. Brenda Bloodgood
27 perc 34. rész Max Planck Florida Institute for Neuroscience
On this episode of Max Planck Florida's Neurotransmissions Podcast Misha and Paul sit down with Dr. Brenda Bloodgood, assistant professor in the Division of Biological Sciences at the University of California San Diego. Hear how Dr. Bloodgood’s path from aspiring undergraduate neuroscientist to professor informs her approach to not only her lab’s research linking gene expression to neural plasticity, but also to her philosophy of teaching and the greater role scientists can play in their communities.
Synaptic Plasticity and Cancer in Intellectual Disabilities with Dr. Claudia Bagni
33 perc 33. rész Max Planck Florida Institute for Neuroscience
On this episode of Max Planck Florida's Neurotransmissions Dr. Paul Evans, former Postdoc in the Yasuda lab and current MPFI Academic Programs Coordinator, and Dr. Audrey Bonnan, Postdoc in the Christie lab, are joined by Dr. Claudia Bagni. Dr. Bagni is the Professor and Chair in Fundamental Neuroscience at the University of Lausanne where her group has been studying the cellular and molecular mechanisms of synaptic plasticity and their dysfunction in inherited intellectual disabilities. Learn about how Dr. Bagni's research has led her beyond neuroscience into cancer research and how she has pursued opportunities to translate her research from the bench to the clinic. Enjoy!
31: Peering into the Fly Brain with Dr. Vivek Jayaraman
38 perc 32. rész Max Planck Florida Institute for Neuroscience
Sometimes studying smaller, simpler problems can give us valuable insights into larger, more complex ones. On this episode of Max Planck Florida's Neurotransmissions podcast, Joe and Dan Wilson, former IMPRS student and current postdoc at Harvard, sit down with Janelia Group Leader Dr. Vivek Jayaraman to discuss his circuitous path from aerospace engineering to neuroscience. Learn how the simplest of circuits, the crab stomatogastric ganglion, inspired him to delve deeper into neural networks, and led him to study the fruit fly.
30: Building Brains with Dr. Oscar Marin
27 perc 31. rész Max Planck Florida Institute for Neuroscience
Can investigating how the neocortex is built further our understanding of the function of the brain? Join Michael and Andre as they sit down with Dr. Oscar Marin, Director and Group Leader at the Centre for Developmental Neurobiology at Kings College London to discuss how the brain is built. In a wide-ranging conversation, they explore the components that come together to build the brain, how programmed cell death may contribute to the normal development of the brain, the contribution of developmental disorders to psychiatric disorders, and adult neurogenesis.
#29 - Modular Motifs of the Neocortex with Dr. Andreas Burkhalter
40 perc 30. rész Max Planck Florida Institute for Neuroscience
Join Joe and Misha as they survey the neocortex with Dr. Andreas Burkhalter, Professor of Anatomy and Neurobiology at Washington University. As they discuss Dr. Burkhalter's path from studying vision in ants and pigeons to his current work studying rodent neocortex learn about the evolutionary development of neocortex, different theories underpinning sensory processing, the newly found modular organization of the rodent cortex.
Episode 28- Interrogating the Cerebellum with Dr. David DiGregorio
38 perc 29. rész Max Planck Florida Institute for Neuroscience
On this podcast, Misha, Joe, and Matthias sit down with Dr. David DiGregorio, group leader of the Dynamic Neuronal Imaging Laboratory at Institut Pasteur, to discuss the cerebellum. From the cerebellum’s role in motor planning to the growing interest in its role in cognitive function, they will explore how Dr. DiGregorio’s model-based approaches are allowing his team to test hypotheses about the cerebellar circuit.
Episode 27: A vision quest with Dr. Michael Stryker
44 perc 28. rész Max Planck Florida Institute for Neuroscience
How does an aspiring poet become one of the pioneers of new model systems for studying the visual cortex? Find out as Joe and Ben sit down with Dr. Michael Stryker, Professor of Physiology at the University of California San Francisco, to chat about his journey through science and how graduate student-mentor relationships have evolved over time.
#26 Theory Meets Experiment with Dr. Judith Hirsch and Dr. Fritz Sommer
56 perc 27. rész Max Planck Florida Institute for Neuroscience
Using whole-cell recording techniques, Judith Hirsch investigates how the early visual pathway helps translate the visual world into a coherent perception. Fritz Sommer takes theoretical and computational approaches to understanding the basis of learning and perception in the brain. In our first dual guest podcast, Joe and Ben sit down with Dr. Hirsch and Dr. Sommer, two neuroscientists who work and live at the intersection of experimental and theoretical neuroscience. Together they explore how different approaches can often lead to divisions in thinking, how theoreticians and experimentalists have and can work together, and the current difficulties and hopeful future of data sharing.
Episode 25: Breaking the diffraction limit with Dr. Stefan Hell
33 perc 26. rész Max Planck Florida Institute for Neuroscience
Episode 25: Breaking the diffraction limit with Dr. Stefan Hell How does one go about breaking the laws of physics? On this podcast, Joe, Misha, and Vered sit down with Dr. Stefan Hell to discuss his path to developing super-resolution light microscopy techniques that allow researchers to see details of biology at a scale never before possible. Discover how Dr. Hell was driven to tackle the fundamental limits of resolution for light micrsocopy leading to the 2014 Nobel Prize in Chemistry, the different approaches taken to super-resolution microscopy, and his new program that is opening up freedom for early career researchers to pursue topics they are passionate about.
#24 Music to our Ears: Birdsong, Speech, and Neural Circuits with Dr. Rich Mooney
50 perc 25. rész Max Planck Florida Institute for Neuroscience
Driven by a lifelong love of music, Rich Mooney's career as a neuroscientist focuses on the circuits that integrate sensory and motor signals in the service of behavior. In a wide ranging interview, Joe, Misha, and Ben sit down with Dr. Mooney to discuss why the songbird is an unparalleled model organism for such a research focus. We also hear about how advances in research tools are leading to a new understanding of how other species integrate motor and auditory signals in the brain, and what this implies about our perception of speech at a philosophical level. Enjoy!
#23: Sunposium 2017: Part 3, Natural Behaviors with Drs. Michael Long and David Anderson
33 perc 24. rész Max Planck Florida Institute for Neuroscience
How neural circuits form the basis of complex natural behaviors is a fundamental question in neuroscience, and from an evolutionary perspective, these circuits enable the survival and reproduction of organisms from generation to generation. In our final live episode from Sunposium 2017, we sit down with two leading experts to discuss their research into behavioral neural mechanisms. First, we talk to Dr. Michael Long from NYU about his work studying vocal communication, and we learn how birdsong and speech can be studied in complementary ways to gain new insights into motor behaviors. We then talk to Dr. David Anderson from Caltech about his work studying the neural basis emotion. He describes how the brain is able to generate internal states that regulate behaviors such as fear and aggression, and how he is able to study these behaviors in both mice and flies to make use of diverse and complementary techniques.
#22: Sunposium 2017: Part 2, Technological innovation with Drs. Ed Boyden & Viviana Gradinaru
36 perc 23. rész Max Planck Florida Institute for Neuroscience
To advance our understanding of the nervous system, we need to know how to ask the right questions about the structure and function of neural circuits. This is often facilitated by new techniques for recording, imaging, and manipulating neural activity. In this episode, we return to our series of interviews from MPFI’s 2017 Sunposium conference. We sit down with Dr. Ed Boyden from MIT and Dr. Viviana Gradinaru from Cal Tech (2016 Peter Gruss Young Investigator Award), two leading innovators in the field, to explore the intersection of tool development and experimental neurobiology.
#21: The Neural Computation of Space, with Dr. Edvard Moser
42 perc 22. rész Max Planck Florida Institute for Neuroscience
"Where are we and where are we going?" Our sense of where we are in the world is one of the most fundamental cognitive elements of our day-to-day lives, and the discovery of our brain's internal system for mapping our physical location is one of the landmark achievements of modern neuroscience. In this episode we sit down Dr. Edvard Moser, one of the three recipients of the 2014 Nobel Prize in Physiology or Medicine for his work discovering the neural computation of our brain's internal "GPS" system. We discuss the organization of this system, as well as many of the mysteries that remain unsolved in understanding the functional circuits involved in forming a neural representation of space.
#20: Live from Sunposium 2017: Part 1, The Value of Scientific Knowledge with Dr. Thomas Südhof
16 perc 21. rész Max Planck Florida Institute for Neuroscience
Live from West Palm Beach, it's Sunposium 2017! Here is Part 1 in a series of conversations we had at MPFI's Sunposium Conference, which is a biennial scientific meeting featuring talks from many renowned names in neuroscience. Misha and Joe sat down with Dr. Thomas Südhof, recipient of the 2013 Nobel Prize in Physiology or Medicine for his work on synaptic vesicle trafficking, to discuss the importance of scientific research in society. Enjoy!
#19: SfN 2016: Part 4, Neural Circuits for Complex Behaviors
42 perc 20. rész Max Planck Florida Institute for Neuroscience
Our series of interviews from SfN 2016 concludes with a grand finale! Two fantastic researchers share their experiences studying neural circuits regulating important behaviors. First, Joe sits down with Dr. Annegret Falkner to discuss her amazing work on aggression circuits, as well as her thoughts on the current academic job market (she has since been hired as a faculty member in the Princeton Department of Neuroscience). Next, Misha talks to Dr. William Giardino from Stanford about his work on the regulation of sleep and wakefulness, and the relevance of this research for understanding neurological and psychiatric disorders. Enjoy!
#18: Smart cerebellums and career decisions with Dr. Kamran Khodakhah
43 perc 19. rész Max Planck Florida Institute for Neuroscience
We’ve heard that an injured cerebellum can make you uncoordinated, but can it also make you mean? Listen to an awesome and engaging interview where Misha, Ben, and first time host Audrey Bonnan learn how the cerebellum interacts with the the rest of the brain from Dr. Kamran Khodakhah, professor and chair in the Department of Neuroscience at the Albert Einstein College of Medicine. Dr. Khodakhah also shares some solid and insightful statistics and advice for career scientists.
#17: Science writing and life living with Dr. Brett Mensh
38 perc 18. rész Max Planck Florida Institute for Neuroscience
In this very special episode, we get to talk with emergency room physician, engineer, neuroscientist, scientific advisor, and person extraordinaire Brett Mensh. As a professional grant writing specialist, Dr. Mensh shares his insights on how to get your ideas funded and papers published by telling compelling stories. We also learn about his unique and diverse career history, and the path that brought him to be a highly successful scientific advisor. All this and more with two brand new co-hosts, Dr. He Zheng and Dr. Paul Evans!
#16: Metabolic Mayhem: Energy Homeostasis with Dr. Jens Bruning
32 perc 17. rész Max Planck Florida Institute for Neuroscience
Everything we do requires energy, so it's not surprising that our brains are wired to regulate how we acquire and use that energy for survival. In this episode, Joe is joined by Dr. Jens Bruning, Director at the Max Planck Institute for Metabolism Research in Cologne, Germany, to discuss how the brain regulates feeding behavior and energy use in the body. Dr. Bruning also describes the surprising ways in which our evolutionary history conflicts with our current lifestyles in a way that contributes to modern day health problems. After hearing this, you won't think about food the same way again!
#15: SfN 2016: Part 3, Sensory-motor Neural Circuits
40 perc 16. rész Max Planck Florida Institute for Neuroscience
Whether you're navigating through a forest, hunting prey, avoiding predators, or listening to a podcast in the gym, behaviors in the world require the coordination of both sensory and motor circuits in the brain. Part 3 in our series of interviews from the 2016 SfN meeting in San Diego gets into science sensory-motor integration. Joe sat down with two great auditory experts, David Schneider and Ross Williamson, who describe their postdoctoral research studying the circuits that govern hearing and motor control. Take a listen!
#14: Neocortex: Organizational and Functional Principles with Dr. Andreas Tolias
29 perc 15. rész Max Planck Florida Institute for Neuroscience
The neocortex is a hallmark of mammalian brain evolution, and the underlying principles that define cortical circuits have captured the attention of neuroscientists for decades. In this episode, we sit down with Andreas Tolias from Baylor College of Medicine to discuss how his lab is unraveling both the cellular organization of the neocortex, as well as the information processing power of cortical circuits. We also welcome first time host, Michael Yetman, to the show!
#13: SfN 2016: Part 2, Beyond the Bench: Exploring Science Careers Outside of the Lab
41 perc 14. rész Max Planck Florida Institute for Neuroscience
For the second installment of our on-the-floor recording from SfN, we find out about some lesser-known opportunities and careers available to PhDs. Misha talks to Dr. Sofia Jurgensen, senior scientist at Sanofi Genzyme and head of the SfN Training Committee about the volunteering opportunities available through the SfN committee system. We also hear from Dr. Lauren Ullrich, Health Program Specialist at NINDS, about her experience working in science advocacy and her current position at the NIH. Finally, Misha talks to Dr. Bridget Queenan, Associate Director of the UCSB Brain Initiative, about her efforts in creating interdisciplinary collaborations for neuroscientists. Tell your friends.
#12: CRISPR/Cas9: A gene editing revolution with Dr. Emmanuelle Charpentier
33 perc 13. rész Max Planck Florida Institute for Neuroscience
In what has been hailed as the discovery of the century, Emmanuelle Charpentier and her colleagues unraveled the molecular machinery of bacterial immune systems and repurposed them into the powerful CRISPR/Cas9 gene editing technology. Since 2012, CRISPR has taken the world by storm, transcending all branches of the biomedical and life sciences. Today, Dr. Charpentier shares the story behind this breakthrough with us, as well as the potential for CRISPR/Cas9 in therapies for diseases ranging from cancer to neurodegeneration.
#11: SfN 2016: Part 1, Scientific Communication with NPR’s Jon Hamilton
27 perc 12. rész Max Planck Florida Institute for Neuroscience
The podcast hit the road to San Diego for the annual SfN meeting and met up with new and old friends to talk all things neuroscience. In this weeks episode, Joe talks with award-winning NPR correspondent Jon Hamilton about his career in science journalism, and what scientists can do to give their work a broader impact to the general public. Then we hear from Misha and fellow podcaster Anthony Lacagnina, host of the amazing Brain Matters Podcast at UT Austin. Listen while they talk about the joys and benefits of science podcasting.
#10: Epilepsy with Dr. Patrick Forcelli
40 perc 11. rész Max Planck Florida Institute for Neuroscience
Epilepsy is a complex group of disorders with a diverse set of causes. We sit down with Georgetown University's Dr. Patrick Forcelli to discuss different forms of epilepsy, as well as his research into the effects of anticonvulsant medications on brain development. We'll also hear about what the epileptic brain can tell us about neural circuits in general.
#9: Dendrites and Data Sharing with Dr. Karel Svoboda
34 perc 10. rész Max Planck Florida Institute for Neuroscience
Neurons share information via synapses, but how do scientists? We talk to the distinguished Dr. Karel Svoboda from Janelia Research Campus about his breakthroughs in understanding synapses, problems with "big data", and the role of machine learning in future scientific progress. We also learn about ways in which open data sharing can benefit science. All of this and more on this special episode of Neurotransmissions!
#8.5: Dr. David Ferster on Writing
11 perc 9. rész Max Planck Florida Institute for Neuroscience
Welcome to a special mini-episode of Neurotransmissions. After our interview with Dr. Ferster, we had and unexpectedly candid and enlightening conversation about communicating Science. Find out why sometimes the science doesn't really start until you put pen to paper.
#8: Visual Computation with Dr. David Ferster
44 perc 8. rész Max Planck Florida Institute for Neuroscience
The mammalian visual cortex performs important transformations of the information that is transmitted from the eye to the brain. We sit down with Dr. David Ferster, Professor Emeritus from Northwestern, to discuss his long career studying the cellular mechanisms of these transformations. We also find out what life after academic retirement is like, and how he's continuing to use his scientific expertise in the private sector to develop new technology for neuroscientists.
#7: Get to know your president! - Development, Experience and Plasticity with Dr. Hollis Cline
20 perc 7. rész Max Planck Florida Institute for Neuroscience
Looking inside the brains of translucent amphibians, Dr. Hollis Cline studies the development and plasticity of the visual system. Join Misha, Joe, and Andre as they get to know more about her research as well her position as the president of the Society for Neuroscience.
#6: Biology and Sexism - Equality for Women in Scientific Careers
30 perc 6. rész Max Planck Florida Institute for Neuroscience
Women are awarded over half of all doctorate degrees in the life sciences, but account for a small fraction of high-ranking academic positions. To investigate this phenomenon, Joe and Misha explore the various barriers and experiences unique to women in science with Dr. Leslie Vosshall of The Rockefeller University, Dr. Na Ji of Janelia Research Campus, and Ellie Hozhabri at the Max Planck Florida Institute for Neuroscience.
#5: The Hedgehog and the Fox - Connectomics, Part 2 with Dr. Tony Movshon
49 perc 5. rész Max Planck Florida Institute for Neuroscience
What can we learn from studying the vast complexity of wiring in the brain? In this week's episode, Professor Movshon explains why a functional perspective is lacking in a connectomics approach that limits our ability to understand what the brain is doing. We'll also hear about how a diverse set of scientific interests can make for a fruitful and enjoyable career in research.
#4: Neurons, Astronomy and Superman - Adaptive Optics with Dr. Na Ji
40 perc 4. rész Max Planck Florida Institute for Neuroscience
How do neuroscientists see through layers of grey matter to produce images of cells that are deeply embedded in living brains? Dr. Na Ji from HHMI's Janelia Research Campus explains how optical tricks from astronomy can be applied to solve this problem. We cover her exciting academic career from China to California and beyond. Tune in to get the inside scoop on the next big advancements in neuroscience.
#3: A Life in Focus: The Journey of Dr. Eric Betzig
57 perc 3. rész Max Planck Florida Institute for Neuroscience
From Cornell to Bell Labs and beyond, Eric Betzig spent an entire career trying to see the unseeable. The optics of conventional microscopes face a fundamental, physical limit on their resolution. Dr. Betzig's quest to break this limit ultimately led to the development of a super-resolution microscopy technique, providing researchers a level of detail in biology and that had never been possible before. Misha, Ben and Joe sit down with him to discuss his incredible life story, and discover how a lauded physicist walked away from a promising career in science, only to return a decade later to achieve great scientific success that earned the 2014 Nobel Prize for Chemistry.
#2: Connectomics - Unraveling a Society of Cells with Dr. Jeff Lichtman
31 perc 2. rész Max Planck Florida Institute for Neuroscience
Humans have 10 times more neurons in our brain than there are people on the earth, so how do these billions of cells manage to all work together? Misha, Ben, and Joe sit down with Dr. Jeff Lichtman, professor of Neuroscience at Harvard University, to talk about his work understanding the complexity of how neurons connect with one another. We discuss recent technological breakthroughs and shortcomings in traditional microscopy, and whether we can transfer our consciousness onto computers.
#1: Basic Science, the Brain, and Going to Mars, with Dr. David Fitzpatrick
39 perc 1. rész Max Planck Florida Institute for Neuroscience
What is basic science, and how is it significant in the realm of brain research and the future progress of our society? Your hosts Joe, Misha, and Ben sit down with Dr. David Fitzpatrick, Scientific Director of the Max Planck Florida Institute for Neuroscience and tackle those questions and more on the first episode of the Neurotransmissions podcast, tackling neuroscience stories from the lab and life - a special episode to celebrate Brain Awareness Week, 2016.
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